Available courses

1. Learning Objectives
Identify the four nitrogenous bases (A, T, C, G) and explain their role as the "alphabet of life".
Describe the physical architecture of the B-form of DNA, including the sugar-phosphate backbone and base-pairing rules.
Analyze how different scientific disciplines (physics, chemistry, and math) contributed to a single biological breakthrough.
Relate the concept of a "single-letter" genetic error to real-world biological outcomes, such as Sickle Cell Anemia.
2. Expected Learning Outcomes
Students will be able to construct a model of DNA using the "spiral staircase" analogy, correctly pairing purines with pyrimidines.
Students will demonstrate an understanding of Chargaff’s Rules by calculating base percentages (e.g., if A=30%, then T=30%).
Students will articulate why DNA must be flexible (like a "rubber ladder") rather than rigid to function within a living cell.

By the end of this module, students will be able to:
Describe the physical dimensions and right-handed helical structure of B-form DNA.
Explain the chemical basis of complementary base pairing and the antiparallel nature of polynucleotide chains.
Identify the components of the DNA backbone and their orientation relative to the nitrogenous bases.
Expected Learning Outcomes
Students will demonstrate an understanding that genetic information is carried in the sequence of bases.
Students will be able to calculate base proportions based on the principle that the amount of G equals C and A equals T.
Students will visualize or tactually identify the major and minor grooves formed by the twisting strands